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J Stroke Cerebrovasc Dis ; 30(1): 105428, 2021 Jan.
Article in English | MEDLINE | ID: covidwho-1023679

ABSTRACT

The SARS-CoV-2 virus causing Coronavirus Disease 2019 (COVID-19) is a global pandemic with almost 30 million confirmed worldwide cases. Prothrombotic complications arising from those affected with severe symptoms have been reported in various medical journals. Currently, clinical trials are underway to address the questions regarding anticoagulation dosing strategies to prevent thrombosis for these critically ill patients. However, given the increasing use of therapeutic anticoagulation in patients admitted with COVID-19 to curtail this prothrombotic state, our institution has witnessed six cases of devastating intracranial hemorrhage as well as thrombosis leading to five fatalities and we examine their hospital course and anticoagulation used.


Subject(s)
Anticoagulants/adverse effects , COVID-19 Drug Treatment , Fibrinolytic Agents/adverse effects , Hospitalization , Intracranial Hemorrhages/chemically induced , Thrombosis/prevention & control , Aged , COVID-19/complications , COVID-19/diagnosis , Fatal Outcome , Female , Humans , Intracranial Hemorrhages/diagnostic imaging , Male , Middle Aged , Thrombosis/diagnosis , Thrombosis/etiology , Treatment Outcome
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